As filed with the Securities and Exchange Commission on March 15, 2022
Registration No. 333-
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
Inozyme Pharma, Inc.
(Exact Name of Registrant as Specified in Its Charter)
Delaware | 38-4024528 | |
(State or Other Jurisdiction of Incorporation or Organization) |
(I.R.S. Employer Identification No.) |
321 Summer Street Suite 400 Boston, Massachusetts |
02210 | |
(Address of Principal Executive Offices) | (Zip Code) |
2020 Stock Incentive Plan
2020 Employee Stock Purchase Plan
(Full Title of the Plan)
Axel Bolte
President and Chief Executive Officer
321 Summer Street
Suite 400
Boston, Massachusetts 02210
(Name and Address of Agent For Service)
(857) 330-4340
(Telephone Number, Including Area Code, of Agent For Service)
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of large accelerated filer, accelerated filer, smaller reporting company, and emerging growth company in Rule 12b-2 of the Exchange Act.
Large accelerated filer | ☐ | Accelerated filer | ☐ | |||
Non-accelerated filer | ☒ | Smaller reporting company | ☒ | |||
Emerging growth company | ☒ |
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐
STATEMENT OF INCORPORATION BY REFERENCE
This Registration Statement on Form S-8, relating to the 2020 Stock Incentive Plan of Inozyme Pharma, Inc. (the Registrant) and the 2020 Employee Stock Purchase Plan of the Registrant, is being filed for the purpose of registering additional securities of the same class as other securities for which a Registration Statement on Form S-8 relating to the 2020 Stock Incentive Plan and the 2020 Employee Stock Purchase Plan has previously been filed and is effective. Accordingly, this Registration Statement incorporates by reference the contents of (i) the Registration Statement on Form S-8, File No. 333-240146, filed with the Securities and Exchange Commission on July 28, 2020 by the Registrant, relating to the Registrants Amended and Restated 2017 Equity Incentive Plan, as amended, 2020 Stock Incentive Plan and 2020 Employee Stock Purchase Plan and (ii) the Registration Statement on Form S-8, File No. 333-254685, filed with the Securities and Exchange Commission on March 25, 2021 by the Registrant, relating to the Registrants 2020 Stock Incentive Plan and 2020 Employee Stock Purchase Plan and, in each case, except for Item 8, Exhibits.
Item 8. | Exhibits |
* | Filed herewith |
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Boston, Commonwealth of Massachusetts, on this 15th day of March, 2022.
INOZYME PHARMA, INC. | ||
By: | /s/ Axel Bolte | |
Axel Bolte | ||
President and Chief Executive Officer |
POWER OF ATTORNEY AND SIGNATURES
We, the undersigned officers and directors of Inozyme Pharma, Inc., hereby severally constitute and appoint Axel Bolte, Henric Bjarke and Stephen DiPalma, and each of them singly, our true and lawful attorneys with full power to them, and each of them singly, to sign for us and in our names in the capacities indicated below, the registration statement on Form S-8 filed herewith and any and all subsequent amendments to said registration statement, and generally to do all such things in our names and on our behalf in our capacities as officers and directors to enable Inozyme Pharma, Inc. to comply with the provisions of the Securities Act of 1933, as amended, and all requirements of the Securities and Exchange Commission, hereby ratifying and confirming our signatures as they may be signed by our said attorneys, or any of them, to said registration statement and any and all amendments thereto.
Pursuant to the requirements of the Securities Act of 1933, this registration statement has been signed by the following persons in the capacities and on the dates indicated.
Signature |
Title |
Date | ||
/s/ Axel Bolte Axel Bolte |
President and Chief Executive Officer, Director (Principal Executive Officer) |
March 15, 2022 | ||
/s/ Stephen DiPalma Stephen DiPalma |
Interim Chief Financial Officer (Principal Financial and Accounting Officer) |
March 15, 2022 | ||
/s/ Douglas Treco Douglas Treco |
Chairman | March 15, 2022 | ||
/s/ Sarah Bhagat Sarah Bhagat |
Director | March 15, 2022 | ||
/s/ Reinaldo Diaz Reinaldo Diaz |
Director | March 15, 2022 | ||
/s/ Martin Edwards Martin Edwards |
Director | March 15, 2022 | ||
/s/ Robert Hopfner Robert Hopfner |
Director | March 15, 2022 | ||
/s/ Edward Mathers Edward Mathers |
Director | March 15, 2022 | ||
/s/ Lynne Sullivan Lynne Sullivan |
Director | March 15, 2022 |
Exhibit 5.1
March 15, 2022
Brian A. Johnson
+1 212 230 8800 (t)
+1 212 230 8888 (f)
wilmerhale.com
Inozyme Pharma, Inc.
321 Summer Street
Suite 400
Boston, Massachusetts 02210
RE: 2020 Stock Incentive Plan; 2020 Employee Stock Purchase Plan
Ladies and Gentlemen:
We have assisted in the preparation of a Registration Statement on Form S-8 (the Registration Statement) to be filed with the Securities and Exchange Commission (the Commission) under the Securities Act of 1933, as amended (the Securities Act), relating to an aggregate of 1,183,436 shares of common stock, par value $0.0001 per share (the Shares), of Inozyme Pharma, Inc., a Delaware corporation (the Company), issuable under the Companys 2020 Stock Incentive Plan and 2020 Employee Stock Purchase Plan (collectively, the Plans).
We have examined the certificate of incorporation and bylaws of the Company, each as amended and restated to date, and originals, or copies certified to our satisfaction, of all pertinent records of the meetings of the directors and stockholders of the Company, the Registration Statement and such other documents relating to the Company as we have deemed material for the purposes of this opinion.
In our examination of the foregoing documents, we have assumed the genuineness of all signatures, the authenticity of all documents submitted to us as originals, the conformity to original documents of all documents submitted to us as certified, photostatic or other copies, the authenticity of the originals of any such documents and the legal competence of all signatories to such documents.
We assume that the appropriate action will be taken, prior to the offer and sale of the Shares in accordance with the Plans, to register and qualify the Shares for sale under all applicable state securities or blue sky laws.
We express no opinion herein as to the laws of any state or jurisdiction other than the state laws of the State of New York, the General Corporation Law of the State of Delaware and the federal laws of the United States of America.
It is understood that this opinion is to be used only in connection with the offer and sale of the Shares while the Registration Statement is in effect.
Please note that we are opining only as to the matters expressly set forth herein, and no opinion should be inferred as to any other matters.
Based on the foregoing, we are of the opinion that the Shares have been duly authorized for issuance and, when the Shares are issued and paid for in accordance with the terms and conditions of the Plans, the Shares will be validly issued, fully paid and nonassessable.
We hereby consent to the filing of this opinion with the Commission in connection with the Registration Statement in accordance with the requirements of Item 601(b)(5) of Regulation S-K under the Securities Act. In giving such consent, we do not hereby admit that we are in the category of persons whose consent is required under Section 7 of the Securities Act or the rules and regulations of the Commission.
Very truly yours,
WILMER CUTLER PICKERING HALE AND DORR LLP | ||
By: | /s/ Brian A. Johnson | |
Brian A. Johnson, a Partner |
Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
We consent to the incorporation by reference in the Registration Statement (Form S-8) pertaining to the 2020 Stock Incentive Plan and the 2020 Employee Stock Purchase Plan of Inozyme Pharma, Inc. of our report dated March 15, 2022, with respect to the consolidated financial statements of Inozyme Pharma, Inc. included in its Annual Report (Form 10-K) for the year ended December 31, 2021, filed with the Securities and Exchange Commission.
/s/ Ernst & Young LLP
Boston, Massachusetts
March 15, 2022
Exhibit 107
Calculation of Filing Fee Tables
Form S-8
(Form Type)
Inozyme Pharma, Inc.
(Exact Name of Registrant as Specified in its Charter)
Table 1Newly Registered Securities
| ||||||||||||||
Security Type |
Security Class Title | Fee Calculation Rule | Amount Registered (1) |
Proposed Maximum Offering Price Per Unit |
Maximum Aggregate Offering Price |
Fee Rate | Amount of Registration Fee | |||||||
Equity |
Common Stock, $0.0001 par value per share | Other | 1,183,436 shares (2) | $5.09 (3) | $6,023,690 (3) | $92.70 per $1,000,000 |
$558.40 | |||||||
Total Offering Amounts |
$6,023,690 | $558.40 | ||||||||||||
Total Fee Offsets |
$0 | |||||||||||||
Net Fee Due |
$558.40 | |||||||||||||
| ||||||||||||||
|
(1) | In accordance with Rule 416 under the Securities Act of 1933, as amended, this registration statement shall be deemed to cover any additional securities that may from time to time be offered or issued to prevent dilution resulting from stock splits, stock dividends or similar transactions. |
(2) | Consists of an additional (i) 946,749 shares issuable under the 2020 Stock Incentive Plan and (ii) 236,687 shares issuable under the 2020 Employee Stock Purchase Plan. |
(3) | Estimated solely for the purpose of calculating the registration fee pursuant to Rules 457(c) and 457(h) of the Securities Act of 1933, as amended, and based upon the average of the high and low prices of the Registrants Common Stock as reported on the Nasdaq Global Select Market on March 10, 2022. |